In the heart, pacemakers are able to work and secrete in a pulsatile manner. A pulsatile secretion pattern is critical to the function of many hormones in order to maintain the delicate homeostatic balance necessary for essential life processes, such as development and reproduction.

What does pulsatile manner mean?

adj beating rhythmically; pulsating or throbbing. ♦ pulsatility n. ponce around n. to behave in a pretentious manner. fashionistas poncing around wearing designer earphones.

What is pulsatile therapy?

Pulsatile administration of GnRH by means of a portable pump is an efficient and practical method for the induction of ovulation as a treatment of infertility in hypothalamic amenorrhea. It represents a replacement therapy based on physiological observations.

What is the meaning of pulsatile in biology?

pulsatile flow. Rhythmic, intermittent propagation of a fluid through a vessel or piping system, in contrast to constant, smooth propagation, which produces laminar flow.

What is pulsatile release of GnRH?

The pulsatile release of GnRH and LH plays an important role in the development of sex function and in the normal regulation of the menstrual cycle. ... One reason for the GnRH secretion in a pulsatile manner is to avoid the down-regulation of the GnRH receptor in the pituitary.

What is PULSATILE SECRETION? What does PULSATILE SECRETION mean? PULSATILE SECRETION meaning

What is pulsatile rhythm?

Pulsatile secretion is a biochemical phenomenon observed in a wide variety of cell and tissue types, in which chemical products are secreted in a regular temporal pattern. ... Pulsatility may function to sensitize target tissues to the hormone of interest and upregulate receptors, leading to improved responses.

What is pulsatile delivery?

Pulsatile drug delivery is defined as the rapid and transient release of certain amount of molecules within a short time period immediately after a predetermined off-released period, i.e., lag time, or these systems have a peculiar mechanism of delivering the drug rapidly and completely after a lag time, i.e., a period ...

What does pulsation mean?

1 : rhythmical throbbing or vibrating (as of an artery) also : a single beat or throb. 2 : a periodically recurring alternate increase and decrease of a quantity (such as pressure, volume, or voltage) Synonyms Example Sentences Learn More About pulsation.

What is the word pulsate mean?

intransitive verb. 1 : to throb or move rhythmically : vibrate. 2 : to exhibit a pulse or pulsation : beat.

What is the meaning of pulsatility?

(ˈpʌlsəˌtaɪl) adj. beating rhythmically; pulsating or throbbing.

What does pulsatile GnRH treatment do?

Pulsatile administration of gonadotropin-releasing hormone (GnRH) is effective in activating the pituitary–gonadal axis. This approach can result in induction of spermatogenesis in approximately 75% of patients with congenital hypogonadotropic hypogonadism who have isolated GnRH and gonadotropin deficiencies (16–18).

What is controlled release tablet?

Controlled Release Drug Dosage Forms encompass both that are controlled to release the drug immediately e.g sublingual tablets or in a delayed or sustained manner such as the Slow-release dosage forms. That is to say. Controlled release dosage forms can be either rapid or slow.

What is pulsatile secretion of GH?

GH IS SECRETED FROM the anterior pituitary in a pulsatile manner as a result of alterations in the secretion of the hypothalamic hormones GH-releasing hormone (GHRH), which stimulates GH synthesis and release, and somatostatin, which inhibits GH release (1, 2).

Is TRH release pulsatile?

This pulsatile pattern of TRH secretion is biologically important, because pituitary thyrotrophs are more responsive to intermittent than continuous TRH stimulation, in terms of TSH secretion (Haus, 2007; Spencer et al., 1980).

What is surge release?

Ovulation is spontaneously triggered about 36-40 hours after blood levels of a hormone called luteinizing hormone (LH) rise. This is called the LH surge. Once released from the ovary, the egg is picked up by and travels down the fallopian tube where it can meet sperm to become fertilized.

What is a throbbing pain?

Throbbing pain is one of the symptoms of a headache. It's a pulsing, beating sensation that happens over and over again. Anyone can get this type of headache, but it's most likely to happen to women. Certain conditions like migraines or caffeine withdrawal can trigger a throbbing headache.

How do you use pulsating in a sentence?

1. The whole room was pulsating with music.
2. I could see the veins in his neck pulsating.
3. Lights were pulsating in the sky.
4. The streets were pulsating with life.
5. Rue St. ...
6. The thumping, pulsating music shook the kitchen walls.

How do you use pulsation in a sentence?

1. Feel the pulsation touching the sun, moon and stars. ...
2. What is the maximal pulsation frequency that can be obtained? ...
3. The period of the pulsation pattern is directly related to the star's intrinsic brightness.

How do you describe pulsation?

The normal pulse rhythm is regular, meaning that the frequency of the pulsation felt by your fingers follows an even tempo with equal intervals between pulsations. If you compare this to music, it involves a constant beat that does not speed up or slow down, but stays at the same tempo.

What is pulsation in the neck?

The carotid arteries take oxygenated blood from the heart to the brain. The pulse from the carotids may be felt on either side of thefront of the neck just below the angle of the jaw. This rhythmic beat is caused by varying volumes of blood being pushed out of the heart toward the extremities.

What is suavity mean?

noun, plural suav·i·ties. a suave or smoothly agreeable quality. suavities, suave or courteous actions or manners; amenities. Also suave·ness .

What is osmotic drug delivery system?

Osmotic drug delivery systems typically consist of a drug core containing osmogen that is coated with a semipermeable membrane. This coating has one or more delivery ports through which a solution or suspension of the drug is released over time.

What is delayed release tablet?

Delayed release (pharmacology), oral medicines that do not immediately disintegrate and release the active ingredient(s) into the body.

Why do we need drug delivery systems?

A drug delivery system is a formulation or a device that enables the introduction of a therapeutic substance in the body and improves its efficacy and safety by controlling the rate, time and place of release of drugs in the body.